[15] Thanh D Hoang, Cara H Olsen, Vinh Q Mai, Patrick W Clyde, Mohamed K M Shakir. hyperthyroidism. The authors delved deeper into the reason why oxidative stress taking place during T4 treatment is particularly linked to lung cancer only: The hypothesis could be that in lungs the increase of hypoxia-induced factor (HIF-1) which is determined by T4 can make oxygen much more available, increasing locally the oxidative stress together with a dangerous angiogenesis stimulation. J Exp Biol 2010, 213:28992911. I invite those interested to read it and perhaps we can have a discussion on this study. In addition, untreated hypothyroidism is associated with a gradual decline in cognitive function and memory. Cancer-related fatigue (CRF) is common in lung cancer survivors and can occur at any point in the care continuum. Garlic Beats Drug in Detoxifying Lead Safely From How Yoga and Acupuncture Enhance HealthNew Resear Health Nuts: Seeds And Nuts You Should Eat Every Day. Endocrinol. Join the Patient & Caregiver Network. [3], An old clinical observation on the relationship between lung cancer and thyroid function reported that patients were characterized by a low concentration of T3 and an increased T4/T3 ratio due to a decrease of 5-monodeiodination (DI). To investigate the magnitude of the possible association between levothyroxine use and cancer risk, this retrospective c Why not simply call it selenium deficiency? When a high-risk patient presents with one or more lung nodules, the path ahead and next steps seems obvious. [8] This means that the amount of LT4 reaching the lungs following an external supplementation cannot to be transformed into LT3 as in the other tissues, and make lungs very vulnerable to possible toxic effects of LT4. Symptoms can include fatigue, shortness of breath with exercise, and decreased ability to exercise. People read a study and think that someone like, perhaps me, is saying "it Causes lung cancer. Acta Endocrinol 1988, 118:460464. elevated TSH, without actually improving the overall physiological situation, nor the patient's subjective experience of well being. It does not necessarily imply one thing caused the other. Ultimately, this latest Italian study is bringing to our attention one of what is likely a wide range of unintended, adverse health effects associated with the overdiagnosis and subsequent overtreatment of hypothyroidism, and the underlying failure of the conventional, largely drug-based paradigm to comprehend the causes and real solutions of disease and human suffering. In the United States, autoimmune thyroid disease (Hashimoto thyroiditis) is the most common cause of hypothyroidism, but globally lack of iodine in the diet is the most common cause. Once I got on the medication, the symptoms disappeared. Find how some diseases can be healed with alternative medicine, and share your experience with There is also compelling research indicating that desiccated thyroid extract (Armour thyroid) results in superior clinical outcomes versus the synthetic hormone, especially as concerns improved body weight. Levothyroxine therapy and serum free thyroxine and free triiodothyronine concentrations. In fact, it is the high levels of T4 that make them more susceptible to cancer. One of the main drawbacks of administering T4 in isolation is the possibility that it will not convert adequately to T3, and will therefore 'back up' causing excessive T4 activity, i.e. Results indicate that treatment with levothyroxine was linked with significantly increased mortality (hazard ratio = 1.19). New Cholesterol Drug Guaranteed to Prematurely Kil Beware the Walgreens travel vaccination scam. [7] They also elaborate on a mechanism of T4-induced lung tissue toxicity: [I]n rats lung the deiodination of LT4 is the lowest compared to all the other tissues. A new study has uncovered a link between the synthetic thyroid hormone (trade name Synthroid) used to treat millions diagnosed with hypothyroidism and lung cancer, bringing to the forefront the harmful role that overdiagnosis and overtreatment plays in nutritional deficiency and chemical exposure related 'diseases.' Levothyroxine therapy and serum free thyroxine and free triiodothyronine concentrations. Maybe because they "treat" only with T4 and not T3? Post by D.ap Tue Feb 21, 2017 6:40 pm "A new study has uncovered a link between the synthetic thyroid hormone (trade name Synthroid) used to treat millions diagnosed with hypothyroidism and lung cancer, bringing to the forefront the harmful role that overdiagnosis and . Thyroid disease is a major public health concern worldwide. 1 The number of individuals with thyroid disorders is expected to continue to grow, having reached approximately 750 million globally in 2012. Physician/Author on Facebook. There is also compelling research indicating that desiccated thyroid extract (Armour thyroid) results in superior clinical outcomes versus the synthetic hormone, especially as concerns improved body weight. I do not believe in random events, of nature or otherwise. I have so much to say about this I could write a book. Compression of the trachea, which may be positional, can occur with nodular goiters and thyroid cancer, and the latter can metastasize to the lungs. Millions of people who were not only wrongly diagnosed with 'cancers' and subsequently aggressively treated for them with chemotherapy, radiation and surgery, are now being told that they would have been better left undiagnosed and untreated. It was the therapist that I went to that referred me to a specialist who ran the correct tests. [1] Hercbergs AH, Ashur-Fabian O, Garfield D: Thyroid hormone and cancer: clinical studies of hypothyroidism in oncology. [11] Wan J, Chai H, Yu Z, Ge W, Kang N, Xia W, Che Y: H1F-1 on angiogenic potential in human small cell carcinoma. [9] [10] [11] Although we should never forget that LT4 is a life-saving thyroid hormone replacement, and that one should not exclude that the pathological reason that leads to the prescription of LT4 could favor the lung cancer development also. This T4 blocking/endocrine-disrupting property of the synthetic form would also activate a negative feedback loop within the endocrine system, further suppressing remaining thyroid function, and resulting in the atrophy of the compromised thyroid, a iatrogenic 'self-fulfilling prophecy' if you will. Desiccated thyroid extract compared with levothyroxine in the treatment of hypothyroidism: a randomized, double-blind, crossover study. I am going to go for a walk with my dog :)). Given the clear role that selenium deficiency plays in preventing the conversion of T4 to the far more biologically active form of thyroid hormone known as triiodothyronine (T3), which can cause an elevation of thyroxine-stimulating hormone (TSH), why call a mineral deficiency-induced decrease in T4 a monolithic disease entity such as "hypothyroidism"? [13] Hollowell JG, Staehling NW, Flanders WD, et al. PLoSone 2011, 11:e27547. I've been on synthroid for 20+ years, scary. As you know, I appreciate people posting links that help us learn more about lung cancer, too. Symptoms. Most of the time, doctors tell patients treated with LT4 that any side effects will be temporary and almost ineluctable, and are usually dealt with through dose reduction. That's all. [14] In other words, you can normalize the main clinically measurable parameter associated with low thyroid function, i.e. [2] Meng R, Tang HY, Westfall J, London D, Cao JH, Mousa SA, Luidens M, Hercbergs A, Davis FB, Davis PJ, et al: Crosstalk between integrin v3 and estrogen receptor- is involved in thyroid hormone-induced proliferation in human lung carcinoma cells. Thanks, I am not suggesting I believe in all that I see. Study: Millions Treated for Hypothyroidism At Risk of Lung Cancer. Gestionar el consentimiento de las cookies. I am convinced that my lung cancer is related to the thyroid/auto immune issues I've had for years. Hypothyroidism can cause depression and, without treatment, the symptoms intensify and directly affect the mental state. [12] Cesarone MR, Belcaro G, Nicolaides AN, Incandela L, De Sanctis MT, Barsotti A: San Valentino epidemiologic project. LOL. A total of 425 inpatients with malignant tumors were treated with ICIs at PUMCH during the study period. For more, visitGreenMedInfo.comand Facebook.com/GreenMedInfo, or sign up forGreenMedInfos free e-Newsletter. Angiology 2000, 51:S65S68. I don't believe there are thousands of people on to high a dose of t4, so why does it feel they are hyper? Link posted. There is also the very real possibility that T4 will not only not properly interact with thyroxine cellular receptors, but will block out what remaining natural levothyroxine the thyroid is still producing (and whose conformational state is far more health-promoting), essentially acting as an endocrine disrupter at the very moment that it is acting as intended as a TSH suppressor. This T4 blocking/endocrine-disrupting property of the synthetic form would also activate a negative feedback loop within the endocrine system, further suppressing remaining thyroid function, and resulting in the atrophy of the compromised thyroid, a iatrogenic self-fulfilling prophecy if you will. In 2020 alone, there were more than 2.2 million new cases and 1.8 million deaths from lung cancer globally. However, the study looked at the incrase of ALL lung cancers, not SCLC, so that data does not correlate with this study. Medical Authoritys System Kills: FDA-Approved Dru Cognitive Impairment, Memory Loss and Alzheimer's Soy Lecithin: How It Negatively Affects Your Healt Cannabis Oil Cures Cancer -Lincoln Horsley's Story New Information Dissolves Illusions About Vaccines Grounding Helps Thin Dangerously Thick Blood and F Tart Cherries Relieve Osteoarthritis Pain, Lieberman's Massive Connections To Big Pharma, Utopian 'Harvest Your Own' Groceries Coming Up. Patients with incomplete information (n = 127), preexisting hypothyroidism or levothyroxine replacement before initiation of ICI therapy (n = 11), or other factors known to contribute to thyroid dysfunction after immunotherapy (n = 17) were excluded (Fig. She wrote about a product called Thyrtophin PMG. In my view the paper isn't worth the pixels used to display it on a screen. In discussing their findings, the authors noted that they could not exclude the possibility that the condition of hypothyroidism could favor the development of lung cancer. Salt, Sugar, Fat: 15 Shocking Facts From the Book Dear Doctor, Do You Really Know What Vaccines Cont Colloidal Gold: Discover the Benefits and Wonders, Scientists Explain Why HPV Vaccines Are Unsafe. In 2011 I switched docs and was put on Armour as he told me Synthroid and the like are poison and they do not work. The authors delved deeper into the reason why oxidative stress taking place during T4 treatment is particularly linked to lung cancer only: The hypothesis could be that in lungs the increase of hypoxia-induced factor (HIF-1) which is determined by T4 can make oxygen much more available, increasing locally the oxidative stress together with a dangerous angiogenesis stimulation. J. Clin. Even acute bouts of stress and subclinical adrenal insufficiency can cause cyclical downshifts in thyroid function. [15] [16]There is also the more logical option of support the bodys thyroid-hormone producing capabilities using the thyroxine precursor L-tyrosine, a basic amino acid with a relatively high margin of safety. This relatively symptom-free reservoir of hypothyroid cases provides a veritable gold mine of potential office visits, billable services and drug prescriptions. Increased sleepiness. [4], More recently DI activity in lung cancer was found to be lower than in peripheral lung tissue.[5]. "A new study has uncovered a link between the synthetic thyroid hormone (trade name Synthroid) used to treat millions diagnosed with hypothyroidism and lung cancer, bringing to the forefront the harmful role that overdiagnosis and overtreatment plays in nutritional deficiency and chemical exposure related 'diseases.' Overtreatment, of course, is the hallmark danger of overdiagnosis. 2 Hypothyroidism is the most common type of thyroid disorder, and women's risk of hypothyroidism is five to eight times higher than that of . Unfortunately, it's quite typical. Desiccated thyroid extract compared with levothyroxine in the treatment of hypothyroidism: a randomized, double-blind, crossover study. The Flu Propaganda Matrix Continues To Promote Fea B Vitamins Slow Alzheimer's and Grey Matter Loss. All the more reason to prescribe T3, I say! At GreenMedInfo.com, we have indexed plenty of peer-reviewed research on over 30 natural substances, including nutrients and minerals, which may help to resolve low thyroid function, and conversely, over 30 unnatural substances, e.g. florence nightingale concept 2 via de boleto See more of Keri Topouzian, D.O. arizona lockdown status today; tiktok unblocked from school; samantha and savannah concepcion PMID: 15253676. I have sent the link that I read today. Now, I will bring it to the attention of my Endocrinologist. The Dangers of Tylenol: Is it Time to for the FDA Chile: Psychiatrist Leads Crusade To Legalize Mari 13 Things Sure To Slow Down Your Metabolism. [12] Cesarone MR, Belcaro G, Nicolaides AN, Incandela L, De Sanctis MT, Barsotti A: San Valentino epidemiologic project. Biomedicine today is awash in controversy associated with the overdiagnosis and overtreatment of asymptomatic populations. In comparison, 62.4% of female and 37% of male . By providing the information contained herein we are not diagnosing, treating, curing, mitigating, or preventing any type of disease or medical condition. I have posted the link now. Why not simply call it selenium deficiency? By accepting all cookies, you agree to our use of cookies to deliver and maintain our services and site, improve the quality of Reddit, personalize Reddit content and advertising, and measure the effectiveness of advertising. Factors found to be associated with mortality were age, senile dementia, congestive heart failure, chronic renal failure, and a history of cerebrovascular disease. I read somewhere about the work done many years ago which was mistakenly read and accepted 28 y/o F Low levels across the board for TSH, T3, and T4, Acid reflux drug linked to more than doubled risk of stomach cancer study, thyroiduk.org - further-reading - thyroid-diagnosis-and-treatment. Assessment of oxidative stress and its balance has not been taken into consideration up to now as it should be.". I don't think so. Endocrinology 2008, 149:22412250. 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Thank you for posting it, I agree we all need as much knowledge as we can get! Or, if fluoride, mercury, or any number of xenobiotic chemicals in the environment requiring selenium-dependent glutathione-mediated detoxification is causing the low thyroid, why call chemical poisoning hypothyroidism? Oops I have just bought my first jar of marmalade in over ten years! Here members can share stories, find important information and learn from the experiences of others like themselves. Study: Millions Treated for Hypothyroidism At Risk of Lung Cancer. The aim of the study was to assess the occurrence and nature of immune-related endocrine adverse events (irAEs) among patients with non-small-cell lung cancer (NSCLC) treated with nivolumab. 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[8] This means that the amount of LT4 reaching the lungs following an external supplementation cannot to be transformed into LT3 as in the other tissues, and make lungs very vulnerable to possible toxic effects of LT4. Clin Cancer Res 2011, 30:77. Obesity epidemic caused by EMF exposures in the ho War on Health - The FDA's Cult of Tyranny. Is so taking anti oxidants might be an idea. Correlation is when two things seem to happen at the same time, in the same place, and/or in the same population. Monaldi Arch Chest Dis 2003, 59:140145. I honestly do not know. Indeed, research indicates that hypothyroid patients treated with T4 replacement, that is sufficient to maintain a normal serum TSH, actually have serum free T4 that is higher than in untreated normal patients and may not result in appropriately normal serum free T3 concentrations. Currently, the best practical approach is to base treatment decisions on the degree of TSH elevation, thyroid autoimmunity, and associated comorbidities. Non-ASPS articles which could be relevant. I'm just saying the evidence presented in this article isn't very strong, and more study is needed to show Synthroid causes lung cancer. As I have lung cancer and just recently was diagnosed hypothyroidI am very interested as to what you have to say about this connection.your personal insight and any books, websites would be appreciated.you may email me if you prefer. Researchers are currently studying. Oops, I just saw that I posted the same article. weight loss, anorexia) was made many years ago together with an over production of both T4 and T3. They then correlated drug sales with cancers, eliminating the contribution of age and smoking for lung cancer risk. This article is copyrighted by GreenMedInfo LLC, 2013, Some features are currently member only features. video where the doc is talking about the study , i wlll link study and video below. Even acute bouts of stress and subclinical adrenal insufficiency can cause cyclical downshifts in thyroid function. 'A new Italian study published in the journal Reproductive Biology and Endocrinology titled, "Levothyroxine and lung cancer in females: the importance of oxidative stress," has raised a concerning possibility: levothyroxine (T4), one of the world's most commonly prescribed forms of hormone replacement, may be raising the risk of lung cancer in millions of men and women being treated for low . Sub-laboratory hypothyroidism and the empirical use of Armour thyroid. View the data on GreenMedInfos Hypothyroidism Research page. Breast cancer has surpassed lung cancer as the most commonly diagnosed cancer worldwide, according to GLOBOCAN. [5]Wawrzynska L, Sakowicz A, Rudzinski P, Langfort R, Kurzyna M: The conversion to triiodothyronine in the lung: comparison of activity of type I iodotironine 5 deiodinase in lung cancer with peripheral lung tissues. Capmatinib (Tabrecta) is the first FDA-approved MET-targeting medication for treating metastatic NSCLC. Log In. Those with the greatest risk of developing thyroid disorders are women who have a family history of the disease. It took over five years before the someone figured out my ongoing symptoms were due to hypothyroidism. Brit Med J 1978, 1:210212. They also noted that oxidative stress is one of the causes of chronic diseases and cancer. The omnipresent environmental contaminant perchlorate, an ingredient in jet fuel, is also a primary cause of hypothyroidism, but is almost never tested for by the conventional endocrinologists in their patient evaluations. Monaldi Arch Chest Dis 2003, 59:140145. Curr Opin Endocrinol Diabetes Obes 2010, 17:432436. [3] Faber J, Poulsen S, Iversen P, Kirkegaard C: Thyroid hormone turnover in patients with small cell carcinoma of the lung. PMID: 11929079, [15] Thanh D Hoang, Cara H Olsen, Vinh Q Mai, Patrick W Clyde, Mohamed K M Shakir. The authors did not study whether individuals who took Synthroid actually developed lung cancer later in life. (February 2002). Article published in Wakeup-World.Com. Angiology 2000, 51:S65S68. Keep checking back for the register link to appear. Whereas a patient who had suboptimal thyroid function, but did not have noticeable symptoms, is suddenly given pharmacological doses of synthetic T4 and suddenly experiences the wide range of acute, adverse health effects associated with a now hyperactive and/or increasingly disrupted thyroid, as a result. But what can be done for patients who are at low Millions of people who were not only wrongly diagnosed with cancers and subsequently aggressively treated for them with chemotherapy, radiation and surgery, are now being told that they would have been better left undiagnosed and untreated. With the 2013 announcement by a National Cancer Institutecommissioned expert panel that a variety of so-called indolent neoplasms such as ductal carcinoma in situ(DCIS) and high-grade prostatic intraepithelial neoplasia (HGPIN), formerly understood to be forms of breast and prostate cancers, respectively, should be renamed to reflect their intrinsic benignity, a veritable sea change is occurring within the conventional medical establishment. rocket fuel, pesticides, fluoride, which induce low thyroid function. Asesora y Consultora Web3 para empresas. Other factors that can trigger thyroid problems include: autoimmune diseases like Hashimoto's or Graves' disease; thyroid surgery; radiation treatments to the neck or upper chest; and certain medications, including interferon alpha and interleukin-2 cancer medications, amiodarone . Nope. [9] [10] [11] Although we should never forget that LT4 is a life-saving thyroid hormone replacement, and that one should not exclude that the pathological reason that leads to the prescription of LT4 could favor the lung cancer development also. I hope that with increased knowledge we will all find the right road. PLoSone 2011, 11:e27547. Finally, they pointed out that T4, which is a synthetic form of thyroid hormone, might be avoided if T3 or the desiccated pig-derived form known as Armour Thyroid was used to control the oxidative-stress producing hydroperoxides. Post [7] Kinoshita S, Sone S, Yamashita T, Tsubura E, Ogura T: Effects of experimental hyperand hypothyroidism on natural defense activities against Lewis lung carcinoma and its spontaneous pulmonary metastases in C57BL/6 mice. However, I'm learning from science writer friends, researchers, and medical professionals that (1) some studies are better designed and carried out than others, and (2) some journalists are more careful about drawing conclusions and writing sensational headlines than others. I was sure that the paper had been discussed here shortly after publication in 2013, but cannot find the thread! Eventually, the decline in thyroid hormone production can result in any of the following: Fatigue and sluggishness. El almacenamiento o acceso tcnico es necesario para crear perfiles de usuario para enviar publicidad, o para rastrear al usuario en una web o en varias web con fines de marketing similares. En 3 minutos recibirs en tu email COMPLETAMENTE GRATIS todo lo que necesitas para aumentar las ventas de tu empresa. Allthewebsites Directory - A niche web directory offering website promotion and other webmaster resources. A distorted idea of human nature is sold when people are treated as "the market. The great open sky of imagination: for those who u Fermented Foods: Top 8 Reasons to Eat Them. [2], The observation that patients with small cell carcinoma of the lung often present symptoms suggestive of hyperthyroidism (i.e. J Endocrinol Invest. Study: Millions Treated for Hypothyroidism At Risk for Lung Cancer A new study has uncovered a link between the synthetic thyroid hormone (trade name Synthroid) used to treat millions diagnosed with hypothyroidism. One of the main drawbacks of administering T4 in isolation is the possibility that it will not convert adequately to T3, and will therefore back up causing excessive T4 activity, i.e. JavaScript is disabled. LifeGivingStore.comRed Light Therapy - Hydrogen Water Generators - Cascara Sagrada - Vitamins, Minerals & Amino Acid Supplements - Cocoa Products - Handcrafted Soaps - Grass Fed Organs & Glandulars - Nano Soma. Tokushima J Exp Med 1991, 38:2535. "Serum TSH, T(4), and thyroid antibodies in the United States population (1988 to 1994): National Health and Nutrition Examination Survey (NHANES III)". I cried with joy when I found out there was something really wrong with me. A new study has uncovered a link between the synthetic thyroid hormone (trade name Synthroid) used to treat millions diagnosed with hypothyroidism and lung cancer, bringing to the forefront the harmful role that overdiagnosis and overtreatment plays in nutritional deficiency and chemical exposure related 'diseases.'. Overtreatment, of course, is the hallmark danger of overdiagnosis. You may not notice signs or symptoms of the disease. Endocrinology 2008, 149:22412250. By rejecting non-essential cookies, Reddit may still use certain cookies to ensure the proper functionality of our platform. If people do not wish to find out all they can about their disease that is fine too. Post author By ; Post date jaripeo hillsboro oregon 2021; what task do they have at camp westerbork on millions treated for hypothyroidism at risk for lung cancer on millions treated for hypothyroidism at risk for lung cancer So I will leave it as a simple thank you for passing this along. There are many links attached. I am having a lot of trouble making any sense of this study. The increasingly global medical-industrial complex has begun to co-opt all aspects of the natural human bodily life cycle, and all the organ systems within it, as potential targets of medical surveillance and intervention, not excluding the human thyroid. I think there is always a lot of confusion with cause and cure. [4] Ratcliffe JG, Stack BH, Burt RW, Radcliffe WA, Spilg WG, Cuthbert J, Kennedy RS: Thyroid function in lung cancer. [14] In other words, you can 'normalize' the main clinically measurable parameter associated with 'low thyroid function,' i.e. I can understand why tennis 123 wrote, "I have so much to say about this I could write a book". They then correlated drug sales with cancers, eliminating the contribution of age and smoking for lung cancer risk. However, that information will still be included in details such as numbers of replies. I have so many women friends and family members who have recently been diagnosed with hypothyroidism and their doctors put them all on Synthyroid.
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