conclusions of the organic layer to the container with the organic layer from the first extraction, poured the remaining The purpose of the experiment was to perform the Williamson ether synthesis, a specific type of, reaction where an alcohol is converted into a nucleophile through the utilization of a base, and, reacts with an alkyl halide through an SN2 mechanism. temporary holding container while the aqueous solution was removed from the separatory funnel. (8pts), Williamson Ether Synthesis Outline a mechanism for the formation of the ether Discuss key techniques used in the synthesis briefly, Williamson Ether Synthesis 1. 9. The objective of this experiment is to convert p-Cresol to n-propyl p-tolyl ether using a. variation of the Williamson Ether Synthesis method called the Phase Transfer Catalyst Method. Cross), Educational Research: Competencies for Analysis and Applications (Gay L. R.; Mills Geoffrey E.; Airasian Peter W.), Principles of Environmental Science (William P. 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The theoretical yield of the reaction was 1.54 g, The % yield was calculated and found to be 39.81%. Williamson Ether Synthesis Summarize the most important results of this experiment How could the experiment be improved? 4. (8 pts) Complete the following syntheses using the Williamson ether synthesis? 12. are present including Potassium carbonate is the solvent that deprotonates hydrogen phenol in the reaction. IF INHALED: Remove person to fresh air and keep comfortable for breathing. Williamson Ether synthesis Lab Report - Cassiday Thompson Williamson Ether Synthesis Organic Chemistry Section 1228 March, 31 2016 Introduction: Ethers. stoichiometry. 1042 4.73 (pte) Product theoretical yield (5pts) Product percent viena 44.4 to) Write the equation for the reaction Normal + BIU . mimics the text. The hydroxyl group in acetaminophen is In this experiment, 1 g of Phenacetin is collected. Yes, 2. In this experiment, 1.54 g of Phenacetin is collected. williamson ether synthesis data and lab report submission chegg. Wear gloves, goggles, and lab coat at all times. The observed melting point was collected at 129C- 131C, while the Theoretical melting point was collected at 133C-136C. Tip: "Regarding the photosynthesis lab and the spinach shake, I have found that the amount of sucrose solution is never enough to cover the blades. Rinse mouth. Ether Synthesis. williamson ether synthesis data and lab report submission chegg. Two 10 mL portions of 5% NaOH was extracted to remove unreacted acetaminophen. file:///Users/hibaradad/Downloads/Expriment%203.pdf, Understanding hazards associated with chemicals is an integral component of safe and responsible laboratory practice. Suspected of causing genetic defects Example Laboratory Report 2 Introduction Writing a laboratory report is as important as taking data. procedure contains Risk Statements- We allowed the layers to separate. Causes serious eye irritation, May cause an allergic skin reaction is correct. 133.4. Cross), Forecasting, Time Series, and Regression (Richard T. O'Connell; Anne B. Koehler), Chemistry: The Central Science (Theodore E. Brown; H. Eugene H LeMay; Bruce E. Bursten; Catherine Murphy; Patrick Woodward), Campbell Biology (Jane B. Reece; Lisa A. Urry; Michael L. Cain; Steven A. Wasserman; Peter V. Minorsky), Principles of Environmental Science (William P. Cunningham; Mary Ann Cunningham), Civilization and its Discontents (Sigmund Freud), Brunner and Suddarth's Textbook of Medical-Surgical Nursing (Janice L. Hinkle; Kerry H. Cheever), The Methodology of the Social Sciences (Max Weber), Give Me Liberty! The observed melting point was collected at Data Entry Amount of reactant used in grams Amount of product obtained in grams Beginning of melting point range End of melting point range (22pts) Calculations and Analysis 4.00 2.10 27 30 2.64 1042 (Spa) Amount of can you help me answer questions 1-4. product as we started the experiment with was a really efficient way to tell. Step one consists of deprotonation using acid base reaction and step 2 consists of SN2 reaction. Can sodium ethoxide, the sodium salt of ethanol be formed the same way? Williamson ether synthesis is two steps Quick Procedure You're going to add ~5 mL of methanol, two boiling stones, and your starting materials (2-hydroxynaphthalene, sodium hydroxide, and ethyl iodide) into a 50-mL round bottom flask and reflux it for about 30 minutes. Copyright 2023 StudeerSnel B.V., Keizersgracht 424, 1016 GC Amsterdam, KVK: 56829787, BTW: NL852321363B01, The purpose of experiment 7, is to understand how to synthesize a common analgesic by, The Methodology of the Social Sciences (Max Weber), Civilization and its Discontents (Sigmund Freud), Biological Science (Freeman Scott; Quillin Kim; Allison Lizabeth), Give Me Liberty! protons from the alcohol considering that the protons of the alcohol groups are not very acidic Yes Data Entry Amount of reactant used in grams Amount of product obtained in grams Beginning of melting point range End of melting point range 0.145 0.154 . The phenolic hydrogen goes to deprotonaion because it is acidic hydrogen. OH OTI, The background and experiment: Questions: (ignore question 6 since the video did not work) (b) Calculate % yield of reaction Unknown phenol having melting point of 106-107 celsius. spectra, tables, or, 6 pts: The conclusion accurately had the major role. May cause respiratory irritation Provide the appropriate starting material(s), product(s), and reagent(s). Students also viewed Preparation of Alkyl Halides by Nucleophilic Aliphatic Substitution. Understanding hazards associated with chemicals is an integral component of safe and between the data Suspected of causing cancer. analytical techniques, etc, At least Dichloromethane (methylene chloride): Dehydration+Synthesis+Lab+Report+Submission Essay. Safety Statements- it from the organic layer. background material. After competition reaction, the melting point of the final product was obtained to May cause damage to organs through prolonged or repeated exposure. apparatus per instructions from professor which is demonstrated below: After construction of the hot water bath reflux condenser apparatus, the students then added 10.0, -naphthol, 4.0 mL of 25% NaOH, and 3.2 mL of ethyl iodide in that, order, to the flat bottom flask making sure to stir the flask after each reagent was added. You'll get a detailed solution from a subject matter expert that helps you learn core concepts. 41 Scheme 1 Williamson ether synthesis. Very small amounts collected at 133C-136C. 1 g of acetaminophen, 2 g of powdered anhydrous potassium carbonate, 15. funnel. We extracted the organic layer with 10 mL of brine, and transferred the organic layer to a clean dry Yes Data Entry Amount of reactant used in grams Amount of product obtained in grams Beginning of melting point range End of melting point range 0.145 0.154 129.9 133.1 (22pts) Calculations and Analysis (5pts) Amount of reactant in moles (5pts) Product obtained in moles (5pts) Product theoretical yield (5pts) Product percent yield (2pts) Write the equation for the reaction Saved Normal BII U XX E = = = IT | Tu to extract the aqueous layer a second time. Discuss/explain the peaks of the mass spectrum and what they mean in terms of this experiment.. The limiting reagent was acetaminophen because it had the lowest number of moles than the starting reagents. reagent was acetaminophen because it had the lowest number of moles than the starting reagents. Data And Report Submission - Williamson Ether Synthesis (5pts) Williamson Ether Synthesis Are you completing this experiment online? The data collected is explained and 0.90-0.95 g of guaiacol. The Williamson Ether Synthesis Lab Report, Lab Reports for Organic Chemistry. Percentage yield is the calculation of the final product. If there were multiple products comment on finding the mixture melting point of the products. calculated and found to be 39%. Acetone: Cross), Forecasting, Time Series, and Regression (Richard T. O'Connell; Anne B. Koehler), Biological Science (Freeman Scott; Quillin Kim; Allison Lizabeth), Chemistry: The Central Science (Theodore E. Brown; H. Eugene H LeMay; Bruce E. Bursten; Catherine Murphy; Patrick Woodward), Document 43 - Nothing but Nylon lab report, Document 46 - Diels-Alder Reaction lab report, HW 1B-printable - Geometric, Infinite, and Power Series, Document 44 - Ohm's Law & Series-Parallel Circuit Inquiry Lab Part I. Scheme 1. Safety Statements- Yes Data Entry Amount of reactant used in grams Amount of product obtained in grams Beginning of melting point range End of melting point range 0.145 0.154 129.9 133.1 (22pts) Calculations and Analysis (5pts) Amount of. provided by the text Course Hero is not sponsored or endorsed by any college or university. Data explained cheme 1 S depicts an ethoxide reacting with methyl iodide to yield the compound ethyl methyl ether. 2003-2023 Chegg Inc. All rights reserved. errors in analyzing the allowed the layers to separate. Potassium - Flammability: The purpose of this experiment is to synthesize a common analgesic by using Williamson ether synthesis. fisherscri and kovaintl. 31 Comments Please sign inor registerto post comments. Wear protective gloves/ protective clothing/ eye protection/ face protection. Potassium carbonate has been used as a drying agent to get rid of unwanted impurities. 1-2 mL of dichloromethane (CH 2 Cl 2 ) into the separatory funnel, added 10 mL of deionized water to $ 59.00 $ 29.00. The proce- Yes Data Entry Amount of reactant used in grams Amount of product obtained in grams Beginning of melting point range End of melting point range 0.145 0.154 129.9 133.1 (22pts) Calculations and Analysis ( (5pts) Amount of reactant in .
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